Associate Scientist/ Scientist I, Analytical and Formulation Development

Company: Dren Bio
Location: San Carlos
Posted on: January 8, 2026

Job Description:

Associate Scientist/ Scientist I, Analytical and Formulation Development About the Company: Dren Bio (the "Company") is a privately held, clinical stage biopharmaceutical company focused on developing therapeutic antibodies for the treatment of cancer, autoimmune and other serious diseases. The Company's management team and scientific advisors have profound expertise covering the discovery and development of specially engineered antibodies. Dren Bio's pipeline encompasses a multitude of programs from its two distinct, wholly-owned technologies. The Company's lead development candidate, DR-01, induces antibody-mediated killing of a specific cell type known to play a key role in various hematologic malignancies and autoimmune disorders. In addition to DR-01, the Company has launched multiple programs from its proprietary Targeted Myeloid Engager and Phagocytosis Platform, a bispecific antibody-based technology that offers a novel mechanism of action focused on selectively engaging myeloid cells (antigen presenting cells) for the targeted depletion of pathologic cells and other disease-causing agents. Function: Analytical and Formulation Development Level: Associate Scientist / Scientist I Location: San Carlos, CA Reporting Manager: Director, Analytical and Formulation Development About the Opportunity: Dren Bio is seeking a highly motivated individual to support antibody characterization and formulation development for the Company’s pipeline programs. The successful candidate will work as a bench Scientist to conduct analytical and bioanalytical method and formulation development and be involved in interactions with contract development and manufacturing organizations (CDMOs). This position offers excellent potential for contribution and visibility at an early-stage company and opportunities for career development. Role and Responsibilities: Develop ELISA and cell based analytical methods for activity and potency testing to support batch release, stability, and formulation development. Develop HPLC, capillary electrophoresis based analytical methods for antibody characterization to support batch release, stability, and formulation development. Apply scientific principles, current technologies, and personal experience to design and execute appropriate experiments to solve challenges in analytical method development. Work closely with colleagues in other functional areas to ensure timely analytical support for cell line, process, and formulation development. Partner with discovery teams to perform manufacturability assessments to support selection of clinical candidates. Contribute to CMC sections in IND submissions and BLA submissions. Facilitate the development of SOPs for various analytical methods and the qualification of methods required for technical transfer to CMO/CRO facilities. Maintain and troubleshoot analytical instrumentation as required and troubleshoot assay performance as needed. Guide junior staff in development work. Document experimental work in notebooks, SOPs and reports. Communicate results and provide updates at internal and external project team meetings. Education, Experience and Qualification Requirements: BS or MS degree in Biochemistry, Analytical Chemistry or related field with: 6 years (for BS) or 4 years (for MS) of experience in the biopharmaceutical industry for Associate Scientist 8 years (for BS) or 6 years (for MS) of experience in the biopharmaceutical industry for Scientist I Required Skills and Experience: Hands-on knowledge of technical scientific principles for most of the following bioanalytical techniques: ELISA and Cell Based Assays. Should be proficient in ELISA and Cell Based Assay methods development and be able to trouble shoot any anomalous internal/external bioassay data. Hands-on knowledge of technical scientific principles for most of the following analytical techniques: HPLC/UPLC (reverse phase, ion exchange, size exclusion), capillary electrophoresis is a plus. Familiarity with techniques to measure protein characteristics such as Tm and stability assessments to support formulation development. Strong analytical and critical thinking skills with the ability to interpret complex data and highly motivated to learn and support the drug development efforts. Experience with performing developability or manufacturability assessments for therapeutic candidates is desirable. Motivated self-starter who can work independently and collaboratively in a dynamic team environment with a proactive attitude. Excellent written and verbal communication skills. Ability to work in a fast-paced environment and the flexibility to align daily work with project needs. Ability to set goals and prioritize tasks and resources to achieve superior work quality and efficiency. Must be well organized, have a strong work ethic, attention to detail and be diligent in data documentation. Salaries, Benefits and Other Employee Perks: Dren Bio strongly believes in investing in, and rewarding, its employees. This philosophy is embodied in the Company’s total rewards program, which includes competitive cash compensation, equity incentive awards, and employer sponsored benefit offerings. The base pay range for this position at commencement of employment is expected to be between $108,000 and $136,000 per year. At Dren Bio, pay ranges are determined by role, level(s), and location. The range displayed in this job posting reflects the minimum and maximum new hire pay for candidates located across all United States job markets. Within the range, individual pay will be determined by work location and additional factors, including job-related skills, experience, and relevant education or training. During the hiring process, Dren Bio’s Human Resources department can share more about the specific pay range based on the market location of the candidate. Employment Practices: Dren Bio is an equal opportunity employer. Employment decisions are based on merit and business needs. Dren Bio will not discriminate against any job applicant because of race, color, national origin, ancestry, gender, sexual orientation, age, religion, creed, physical or mental disability, gender identity, medical condition, pregnancy, marital status, veteran status, or any other characteristic protected by federal, state or local law.

Keywords: Dren Bio, West Sacramento , Associate Scientist/ Scientist I, Analytical and Formulation Development, Science, Research & Development , San Carlos, California