Director, Data Systems and Clinical Programming
Company: Alumis Inc.
Location: South San Francisco
Posted on: March 22, 2026
|
|
|
Job Description:
Alumis Inc. is a precision medicines company with the mission to
transform the lives of patients with autoimmune diseases. Even with
treatment innovations of the last two decades, many patients with
immunologic conditions continue to suffer - our goal is to
fundamentally change the outcomes for these patients. The Director,
Data Systems (DS) and Clinical Programming (CP) will be responsible
for leading and managing the Clinical Programming function within
Data Management (DM). This position will report to the VP, Data
Management and Clinical Programming. Responsibilities: Lead and
manage the Data Systems and Clinical Programming function within DM
Drive the implementation of various technology solutions to augment
existing DM processes, optimize efficiency and enhance overall data
quality assurance Lead and/or participate in AI-related initiatives
for DM Develop and implement strategies for optimizing data flow,
database builds, and integration of external technologies. Oversee
the validation of the EDC platform, ensuring ongoing system
optimization. Manage relationships with key external vendors,
ensuring alignment with organizational goals. Ensure compliance
with all relevant data privacy regulations and maintain the
security of clinical trial data. Ensure DS&CP project
deliverables are completed on time and in accordance with quality
standards and regulatory requirements. Collaborate with other
departments to align data strategy with broader organizational
goals and objectives. Mentor and develop team members, fostering a
culture of continuous learning and growth within the team. Oversee
all SAS clinical programming requests and standardize the clinical
programming specification development process. Develop and/or
maintain Alumis’ standard CRFs and standard edit checks, inclusive
of indication-specific standards. Develop DS&CP SOPs and Work
Instructions. Lead the development and/or maintenance of standard
vendor Data Transfer Agreements (DTAs). Oversee the development and
execution of technical initiatives within DM, including the
implementation of key data visualizations and dashboards for DM,
such as Clean Patient Tracking, data currency, and rolling batch
freeze progress. Integrate the usage of data analytics within DM to
further optimize current processes. Provide strategic oversight of
high-priority projects, including database builds, user access
management, and the release of system updates. Participate in EDC,
IRT and eCOA User Acceptance Testing (UAT) Ensure accurate
development and execution of data integrations between EDC, IXRS or
additional external vendor data sources Ensure DS&CP
study-specific documentation is in an inspection-ready state and
represent the DS&CP function in inspections as applicable.
Represent DS&CP in cross-functional meetings as applicable Act
as a key stakeholder in developing and executing strategies to
accelerate drug development through innovative data management
practices. Qualifications: 12 years of relevant experience and has
earned a BS or equivalent degree; MS or MBA a plus Experience
supporting Ph I-IV clinical trials, both in-house and through CRO
partners Strong knowledge and experience in EDC and other key
technologies (e.g., IXRS, data visualization) Proficiency in CDISC
standards (CDASH, SDTM, ADaM) Experience with SAS, SQL and/or other
clinical programming tools Proficiency in clinical research
regulations and guidance, including FDA CFR and ICH GCP Depth of
experience across all aspects of DM, including but not limited to:
CRF and database development, data quality assurance and analytics,
data transfer management, vendor management, DM study documentation
and inspection readiness. Strong understanding of the application
of MedDRA and WHO Drug clinical data coding classification systems
Strong interpersonal, organizational, and communication (oral and
written) skills Demonstrated ability to cultivate strong working
relationships with internal and external colleagues. Logical
thinking, attention to detail and accuracy, strong organizational
skills, and problem-solving abilities Ability to prioritize and to
adapt quickly to changing business conditions with a “can-do”
attitude Capable of proactively identifying project challenges and
risks and proposing appropriate and strategic solutions to issues.
Willing to travel if required Alumis Values • We Elevate • We
Challenge • We Nurture This position is located in South San
Francisco, CA and employees are expected to be onsite
Tuesday-Thursday. Open to remote applicants with requirement to be
onsite 1-2x a quarter. The salary range for this position is
$200,000 USD to $225,000 USD annually. This salary range is an
estimate, and the actual salary may vary based on the Company’s
compensation practices. Alumis Inc. is an equal opportunity
employer.
Keywords: Alumis Inc., West Sacramento , Director, Data Systems and Clinical Programming, IT / Software / Systems , South San Francisco, California
